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6-CHLORO-2-(4-ETHYLPHENYL)QUINOLINE-4-CARBOXYLICACID synthesis

1synthesis methods
17630-76-1 Synthesis
5-Chloroisatin

17630-76-1
272 suppliers
$6.00/5g

6-CHLORO-2-(4-ETHYLPHENYL)QUINOLINE-4-CARBOXYLICACID

897559-96-5
8 suppliers
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Yield:897559-96-5 68%

Reaction Conditions:

with potassium hydroxide in ethanol;water; for 48 h;Inert atmosphere;Reflux;

References:

Das, Priyabrata;Deng, Xiaoyi;Zhang, Liang;Roth, Michael G.;Fontoura, Beatriz M.A.;Phillips, Margaret A.;De Brabander, Jef K. [ACS Medicinal Chemistry Letters,2013,vol. 4,# 6,p. 517 - 521] Location in patent:supporting information