9-METHYL-6-THIOPURINE synthesis

4synthesis methods

Product Name:9-METHYL-6-THIOPURINE
CAS Number:1006-20-8
Molecular formula:C6H6N4S
Molecular Weight:166.2

2346-74-9 Synthesis

2346-74-9
100 suppliers
$60.00/50mg

1006-20-8
5 suppliers
inquiry

Yield:1006-20-8 95%

Reaction Conditions:

with thiourea in ethanol at 100; for 3 h;

Steps:

1 Example 1:

Prepare a solution of compound 1b in EtOH,To a solution of compound 1b (338 mg, 2.0 mmol) in EtOH (10 mL) was added commercially available thiourea (228 mg, 3 mmol),The reaction was heated to 100°C with stirring and refluxing for 3 hours.After the TCL detection reaction was completed, suction filtration and washing the precipitate with anhydrous EtOH,Spin dry to give compound 2b, 317 mg (white solid), yield 95%.

References:

CN111333651,2020,A Location in patent:Paragraph 0033-0036

52602-68-3 Synthesis