![](/CAS/GIF/905273-56-5.gif)
diMethyl 6-(trifluoroMethyl)pyridine-2,3-dicarboxylate synthesis
- Product Name:diMethyl 6-(trifluoroMethyl)pyridine-2,3-dicarboxylate
- CAS Number:905273-56-5
- Molecular formula:C10H8F3NO4
- Molecular Weight:263.17
![2-TRIFLUOROMETHYLQUINOLINE](/CAS/GIF/347-42-2.gif)
347-42-2
134 suppliers
$20.00/100mg
![Iodomethane](/CAS/GIF/74-88-4.gif)
74-88-4
341 suppliers
$15.00/10g
![diMethyl 6-(trifluoroMethyl)pyridine-2,3-dicarboxylate](/CAS/GIF/905273-56-5.gif)
905273-56-5
10 suppliers
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Yield:905273-56-5 28%
Reaction Conditions:
Stage #1: 2-trifluoromethyl-quinolinewith ruthenium(III) chloride monohydrate;water;periodic acid in tetrachloromethane;acetonitrile at 20;
Stage #2: methyl iodidewith caesium carbonate at 20;
References:
Pinard, Emmanuel;Alberati, Daniela;Bender, Markus;Borroni, Edilio;Brom, Virginie;Burner, Serge;Fischer, Holger;Hainzl, Dominik;Halm, Remy;Hauser, Nicole;Jolidon, Synse;Lengyel, Judith;Marty, Hans-Peter;Meyer, Thierry;Moreau, Jean-Luc;Mory, Roland;Narquizian, Robert;Norcross, Roger D.;Schmid, Philipp;Wermuth, Roger;Zimmerli, Daniel [Bioorganic and Medicinal Chemistry Letters,2010,vol. 20,# 23,p. 6960 - 6965] Location in patent:scheme or table