tert-Butyl 7-fluoro-6-nitro-3,4-dihydroisoquinoline-2(1H)-carboxylate synthesis

6synthesis methods

Product Name:tert-Butyl 7-fluoro-6-nitro-3,4-dihydroisoquinoline-2(1H)-carboxylate
CAS Number:912846-67-4
Molecular formula:C14H17FN2O4
Molecular Weight:296.29

912878-83-2 Synthesis

7-Fluoro-6-nitro-1,2,3,4-tetrahydroisoquinoline

912878-83-2
20 suppliers
$45.00/10mg

24424-99-5 Synthesis

24424-99-5
820 suppliers
$13.50/25G

tert-Butyl 7-fluoro-6-nitro-3,4-dihydroisoquinoline-2(1H)-carboxylate

912846-67-4
31 suppliers
$70.00/100mg

Yield:912846-67-4 76%

Reaction Conditions:

with triethylamine in 1,4-dioxane at 20;

References:

Watson, Nigel S.;Adams, Carl;Belton, David;Brown, David;Burns-Kurtis, Cynthia L.;Chaudry, Laiq;Chan, Chuen;Convery, Máire A.;Davies, David E.;Exall, Anne M.;Harling, John D.;Irvine, Stephanie;Irving, Wendy R.;Kleanthous, Savvas;McLay, Iain M.;Pateman, Anthony J.;Patikis, Angela N.;Roethke, Theresa J.;Senger, Stefan;Stelman, Gary J.;Toomey, John R.;West, Robert I.;Whittaker, Caroline;Zhou, Ping;Young, Robert J. [Bioorganic and Medicinal Chemistry Letters,2011,vol. 21,# 6,p. 1588 - 1592] Location in patent:scheme or table

7-Fluoro-6-nitro-1,2,3,4-tetrahydroisoquinoline hydrochloride

912846-66-3
29 suppliers
$407.00/250mg

24424-99-5 Synthesis

24424-99-5
820 suppliers
$13.50/25G

912846-67-4
31 suppliers
$70.00/100mg

References

912846-63-0 Synthesis

2,2,2-Trifluoro-N-[2-(4-fluorophenyl)-ethyl]acetamide

912846-63-0
14 suppliers
inquiry

912846-67-4
31 suppliers
$70.00/100mg

References

Ethanone, 2,2,2-trifluoro-1-(7-fluoro-3,4-dihydro-6-nitro-2(1H)-isoquinolinyl)-

912846-65-2
2 suppliers
inquiry

912846-67-4
31 suppliers
$70.00/100mg

References

2,2,2-trifluoro-1-(7-fluoro-3,4-dihydro-1H-isoquinolin-2-yl)ethanone

912846-64-1
4 suppliers
inquiry

912846-67-4
31 suppliers
$70.00/100mg

References