ChemicalBook CAS DataBase List 4-[4-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-pyridin-2-yl]-piperazine-1-carboxylic acid tert-butyl ester

4-[4-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-pyridin-2-yl]-piperazine-1-carboxylic acid tert-butyl ester synthesis

5synthesis methods

Product Name:4-[4-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-pyridin-2-yl]-piperazine-1-carboxylic acid tert-butyl ester
CAS Number:936250-21-4
Molecular formula:C20H32BN3O4
Molecular Weight:389.3

24424-99-5 Synthesis

24424-99-5
820 suppliers
$13.50/25G

2-(Piperazin-1-yl)pyridine-4-boronic acid, pinacol ester

957198-31-1
39 suppliers
$60.00/100mg

4-[4-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-pyridin-2-yl]-piperazine-1-carboxylic acid tert-butyl
ester

936250-21-4
45 suppliers
$110.00/1g

Yield:936250-21-4 100%

Reaction Conditions:

with triethylamine in tetrahydrofuran at 20;Inert atmosphere;

References:

Bayliss, Tracy;Robinson, David A.;Smith, Victoria C.;Brand, Stephen;McElroy, Stuart P.;Torrie, Leah S.;Mpamhanga, Chido;Norval, Suzanne;Stojanovski, Laste;Brenk, Ruth;Frearson, Julie A.;Read, Kevin D.;Gilbert, Ian H.;Wyatt, Paul G. [Journal of Medicinal Chemistry,2017,vol. 60,# 23,p. 9790 - 9806]