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ChemicalBook CAS DataBase List IMidazo[1,2-b]pyridazine, 3-[2-(triMethylsilyl)ethynyl]-

IMidazo[1,2-b]pyridazine, 3-[2-(triMethylsilyl)ethynyl]- synthesis

3synthesis methods
-

Yield:943320-60-3 82%

Reaction Conditions:

with [1,1'-bis(diphenylphosphino)ferrocene]dichloropalladium(II);copper (I) iodide in triethylamine;acetonitrile at 80; for 4 h;Inert atmosphere;Sonogashira Cross-Coupling;

References:

Xie, Zhicheng;Wu, Bing;Liu, Yingqiang;Ren, Wenming;Tong, Linjiang;Xiang, Caigui;Wei, Aihuan;Gao, Yuanzhuo;Zeng, Limin;Xie, Hua;Tang, Wei;Hu, Youhong [Journal of Medicinal Chemistry,2020,vol. 63,# 3,p. 1397 - 1414]