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(E)-3-(4-CHLOROPHENYL)-1-[2-(4-CHLOROPHENYL)-4-METHYL-1,3-THIAZOL-5-YL]-2-PROPEN-1-ONE synthesis

3synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1.1: ethanol / 3 h / Heating
1.2: ammonia / H2O
2.1: 55 percent / 40 percent KOH / ethanol / 48 h / 20 °C

References:

Dengle;Ingle;Bondge;Mane [Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry,1999,vol. 38,# 3,p. 390 - 393]