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ChemicalBook CAS DataBase List Acetaminophen Impurity B
98966-17-7

Acetaminophen Impurity B synthesis

3synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 5 steps
1: copper(l) iodide; potassium phosphate / N,N-dimethyl-formamide / 80 °C
2: acetic acid / 70 °C
3: potassium carbonate / acetone / 20 °C / Cooling with ice
4: tetrakis(triphenylphosphine) palladium(0); potassium phosphate / tert-butyl alcohol / 48 h / 110 °C
5: 10% Pd/C / methanol / 20 °C / Inert atmosphere

References:

CN115232022,2022,A

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