alpha-L-Xylopyranose (9CI) synthesis
1synthesis methods
- Product Name:alpha-L-Xylopyranose (9CI)
- CAS Number:7296-58-4
- Molecular formula:C5H10O5
- Molecular Weight:150.13
Yield:28 % de
Reaction Conditions:
Stage #1: D-sorbitolwith hydrogenchloride;benzaldehyde in water at 0 - 20;Inert atmosphere;
Stage #2: with sodium periodate in water at 0 - 20; for 0.5 h;
Stage #3: with acetic acid in water;Inert atmosphere;Heating;Overall yield = 75 percent; Overall yield = 23 g;
References:
Bai, Bing;Liu, Yu-Hsuan;Lowary, Todd L.;Shen, Ke [Angewandte Chemie - International Edition,2021,vol. 60,# 47,p. 24859 - 24863][Angew. Chem.,2021,vol. 133,# 47,p. 25063 - 25067] Location in patent:supporting information