Sorbitol synthesis

7synthesis methods

Product Name:Sorbitol
CAS Number:50-70-4
Molecular formula:C6H14O6
Molecular Weight:182.17

Sorbitol is manufactured by hydrogenation of glucose with hydrogen and active nickel catalyst. It is commercially available as 70% syrup or as a pure white powder.

50-99-7 Synthesis

50-99-7
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$6.00/25g

50-70-4
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$5.00/10g

Yield:50-70-4 100%

Reaction Conditions:

with hydrogen in water at 120; under 15001.5 Torr; for 1 h;

Steps:

11 Example: 11

To 0.5 g of glucose in 40 ml of H20, HRO/Na-β catalyst (50 mg) was added in a reactor vessel. The reactor vessel was then heated at 120 °C for 1 h under H2 pressure (20 bar). After completion of the reaction, the catalyst was separated by using centrifuge and the obtained clear product mixture was analyzed by UHPLC. The reaction gave 100% conversionglucose with 100% yield of sorbitol.

References:

WO2017/60922,2017,A1 Location in patent:Page/Page column 13; 20