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ChemicalBook CAS DataBase List ANGIOTENSIN I/II (4-8)

ANGIOTENSIN I/II (4-8) synthesis

4synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1: 1.) 2-chlorotrityl chloride resin, (i-Pr)2EtN, 2-4.) a)piperidine, b) DCC, HOBt, 5.) AcOH, TFE / solid phase peptide synthesis
2: TFA, anisole / CH2Cl2

References:

Matsoukas;Hondrelis;Agelis;Barlos;Gatos;Ganter;Moore;Moore [Journal of Medicinal Chemistry,1994,vol. 37,# 18,p. 2958 - 2969]

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