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ChemicalBook CAS DataBase List B-PABA

B-PABA synthesis

3synthesis methods
-

Yield:6929-40-4 80%

Reaction Conditions:

Stage #1: 5-[(3AS,4S,6AR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoic acidwith triethylamine;methyl chloroformate in N,N-dimethyl-formamide at -5 - 25; for 0.5 h;
Stage #2: 4-amino-benzoic acidwith triethylamine in tetrahydrofuran;N,N-dimethyl-formamide at 25;Cooling with ice;

References:

Alwash, Ameer H.;Naser, Noor Hatef;Zalzala, Munaf H. [Egyptian Journal of Chemistry,2022,vol. 65,# 10,p. 83 - 99]

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