ChemicalBook CAS DataBase List Bis(2-methyl-3-furyl)disulfide

Bis(2-methyl-3-furyl)disulfide synthesis

4synthesis methods

Product Name:Bis(2-methyl-3-furyl)disulfide
CAS Number:28588-75-2
Molecular formula:C10H10O2S2
Molecular Weight:226.32

28588-74-1 Synthesis

28588-74-1
310 suppliers
$6.00/250mg

28588-75-2
251 suppliers
$7.00/1g

Yield:28588-75-2 93%

Reaction Conditions:

with tert.-butylnitrite;oxygen in 1,2-dichloro-ethane at 50; under 760.051 Torr; for 4 h;Sealed tube;Green chemistry;

Steps:

Typical procedure for disulfides (2a)
General procedure: A sealed tube (90 mL) equipped with a magnetic stirring bar and an O₂ balloon was charged with dichloroethane (DCE, 20 mL), thiophenol (1a, 4 mmol, 0.44 g) and TBN (0.16 mmol, 4 mol%, 19.2 mL). Then the tube was placed in an oil bath, which was preheated to 50°C. The mixture was stirred for 1 h until starting material was completely consumed as monitored by GC and TLC. After removing the solvent, the residue was purified by column chromatography on silica gel to give the desired diphenyl disulfide (2a, 90%, 0.394 g) as a white solid.

References:

Yi, Shan-Li;Li, Mei-Chao;Hu, Xin-Quan;Mo, Wei-Min;Shen, Zhen-Lu [Chinese Chemical Letters,2016,vol. 27,# 9,p. 1505 - 1508]

FullText