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915411-11-9

Boronic acid, B-(2,3-dihydro-1H-inden-4-yl)- synthesis

4synthesis methods
-

Yield:915411-11-9 65.7%

Reaction Conditions:

Stage #1: Triisopropyl borate;4-bromo-2,3-dihydro-1H-indene in tetrahydrofuran at -78; for 0.5 h;Inert atmosphere;
Stage #2: with n-butyllithium in tetrahydrofuran;hexane at -78; for 0.333333 h;Inert atmosphere;

References:

WO2020/35031,2020,A1 Location in patent:Paragraph 0782