C5E1 synthesis
- Product Name:C5E1
- CAS Number:6196-58-3
- Molecular formula:C7H16O2
- Molecular Weight:132.2
110-53-2
406 suppliers
$13.69/5g
107-21-1
1317 suppliers
$10.00/25g
6196-58-3
24 suppliers
$402.00/1g
Yield:6196-58-3 55%
Reaction Conditions:
Stage #1: ethylene glycolwith sodium at 80;
Stage #2: 1-Bromopentane at 80 - 100; for 4 h;
Steps:
1
Sodium metal (0.6 g, 0.025 mmol) was added to ethylene glycol 1 (5 g, 0.083 mmol) at room temperature and heated at 80 °C. Then, 1-bromopentane 2 (3.7 g, 0.025 mmol) was added to the reaction mixture at 100°C and the reaction mixture was continued to stir for 4 h. The mixture was filtered to remove inorganic materials and diluted with ice water (200 mL), extracted with ethyl acetate (2 x 200 mL). Organic layer was washed with brine solution, dried (Na2SO4) and concentrated to get pure 2-(pentyl oxy) ethan-1-ol 3 (2.2 g, 0.0186 mmol, 55%) as yellow liquid. TLC system: 10 % Methanol in dichloromethane - Rf: 0.5
References:
WO2018/200425,2018,A1 Location in patent:Paragraph 00334
75-21-8
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$39.10/1mL
71-41-0
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$10.00/25mL
6196-58-3
24 suppliers
$402.00/1g
96-49-1
490 suppliers
$6.00/100g
71-41-0
427 suppliers
$10.00/25mL
6196-58-3
24 suppliers
$402.00/1g
75-21-8
222 suppliers
$39.10/1mL
71-41-0
427 suppliers
$10.00/25mL
1941-84-0
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6196-58-3
24 suppliers
$402.00/1g
107-21-1
1317 suppliers
$10.00/25g
109-52-4
332 suppliers
$10.60/1gm:
6196-58-3
24 suppliers
$402.00/1g
16179-36-5
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