CCT251455 synthesis
- Product Name:CCT251455
- CAS Number:1400284-80-1
- Molecular formula:C26H26ClN7O2
- Molecular Weight:503.98
![t-butyl 6-bromo-2-(1-methyl-1H-pyrazol-4-yl)-1H-pyrrolo[3,2-c]pyridine-1-carboxylate](/CAS/20180703/GIF/1400286-74-9.gif)
Yield:1400284-80-1 60%
Reaction Conditions:
with tris-(dibenzylideneacetone)dipalladium(0);caesium carbonate;4,5-bis(diphenylphosphino)-9,9-dimethylxanthene in N,N-dimethyl acetamide at 80; for 3 h;Inert atmosphere;
References:
Naud, Sébastien;Westwood, Isaac M.;Faisal, Amir;Sheldrake, Peter;Bavetsias, Vassilios;Atrash, Butrus;Cheung, Kwai-Ming J.;Liu, Manjuan;Hayes, Angela;Schmitt, Jessica;Wood, Amy;Choi, Vanessa;Boxall, Kathy;Mak, Grace;Gurden, Mark;Valenti, Melanie;De Haven Brandon, Alexis;Henley, Alan;Baker, Ross;McAndrew, Craig;Matijssen, Berry;Burke, Rosemary;Hoelder, Swen;Eccles, Suzanne A.;Raynaud, Florence I.;Linardopoulos, Spiros;Van Montfort, Rob L. M.;Blagg, Julian [Journal of Medicinal Chemistry,2013,vol. 56,# 24,p. 10045 - 10065]
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