CHEMBRDG-BB 4023259 synthesis
1synthesis methods
- Product Name:CHEMBRDG-BB 4023259
- CAS Number:58758-45-5
- Molecular formula:C11H10O3
- Molecular Weight:190.2
Yield:58758-45-5 96%
Reaction Conditions:
Stage #1: 3-methoxy-2-hydroxybenzaldehydewith potassium carbonate in N,N-dimethyl-formamide at 20; for 0.25 h;Inert atmosphere;
Stage #2: propargyl bromide in N,N-dimethyl-formamide at 20;Inert atmosphere;
References:
Vedachalam, Seenuvasan;Wong, Qian-Ling;Maji, Biswajit;Zeng, Jing;Ma, Jimei;Liu, Xue-Wei [Advanced Synthesis and Catalysis,2011,vol. 353,# 2-3,p. 219 - 225] Location in patent:supporting information; experimental part