![](/CAS/GIF/51481-61-9.gif)
Cimetidine synthesis
- Product Name:Cimetidine
- CAS Number:51481-61-9
- Molecular formula:C10H16N6S
- Molecular Weight:252.34
![N-CYANO-N',S-DIMETHYLISOTHIOUREA](/CAS/GIF/5848-24-8.gif)
5848-24-8
50 suppliers
$56.00/10g
![Mercury chloride](/CAS/GIF/7487-94-7.gif)
7487-94-7
6 suppliers
$21.00/5g
![4-[[(2-aminoethyl)thio]methyl]-5-methylimidazole](/CAS/GIF/38585-67-0.gif)
38585-67-0
20 suppliers
$420.00/5g
![Cimetidine](/CAS/GIF/51481-61-9.gif)
51481-61-9
561 suppliers
$5.00/100mg
Yield:-
Reaction Conditions:
with potassium carbonate in pyridine;N-methyl-acetamide;
Steps:
7 EXAMPLE 7
EXAMPLE 7 When N-cyano-N',S-dimethylisothiourea is treated with mercuric chloride in pyridine and the mixture added to a mixture of 2-((5-methyl-4-imidazolyl)methylthio)ethylamine and potassium carbonate in dimethylformamide the product is N-cyano-N'-methyl-N"-[2((5-methyl-4-imidazolyl)methylthio)-ethyl]guanidine.
References:
US4049671,1977,A