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Cyclohexanamine, N,N,4-trimethyl-, trans- synthesis

4synthesis methods
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Yield:18 % de

Reaction Conditions:

with hydrogen;scandium tris(trifluoromethanesulfonate) in ethanol at 50; under 760.051 Torr;Catalytic behavior;Schlenk technique;Overall yield = 86 percentChromat.; stereoselective reaction;Reagent/catalyst;Concentration;Solvent;

References:

Miyamura, Hiroyuki;Kobayashi, Shū [Angewandte Chemie - International Edition,2022,vol. 61,# 38,art. no. E202201203][Angew. Chem.,2022,vol. 134,# 38] Location in patent:supporting information