ChemicalBook CAS DataBase List D-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid

D-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid synthesis

2synthesis methods

Product Name:D-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid
CAS Number:103733-65-9
Molecular formula:C10H11NO2
Molecular Weight:177.2

81477-94-3 Synthesis

N-(Diphenylmethylene)glycerine tert-butyl ester

81477-94-3
260 suppliers
$6.00/1g

91-13-4
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$14.00/1g

D-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid

103733-65-9
252 suppliers
$5.00/100mg

Yield:103733-65-9 82%

Reaction Conditions:

Stage #1: N-(diphenylmethylene)glycine tert-butyl ester;α,α'-dibromo-o-xylenewith (S,S)-3,4,5-F₃-Ph-NAS-Br in potassium hydroxide;toluene at 0; for 6 h;
Stage #2: with hydrogenchloride in tetrahydrofuran;
Stage #3: with sodium hydrogencarbonate

References:

Ooi;Takeuchi;Maruoka [Synthesis,2001,# 11,p. 1716 - 1718]

103733-65-9
252 suppliers
$5.00/100mg

115-11-7
228 suppliers
$45.00/25g

103733-65-9
252 suppliers
$5.00/100mg

References

D-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid Related Search:

1,2,3,4-Tetrahydroquinoline Tetrahydrofuran Isoquinoline-1-carboxylic acid 1,2,3,4-Butanetetracarboxylic acid (3S)-2-CARBOBENZOXY-1,2,3,4-TETRAHYDROISOQUINOLINE-3-CARBOXYLIC ACID BOC-7-HYDROXY-D-TIC-OH 1,2,3,4-TETRAHYDRO-ISOQUINOLINE-1-CARBOXYLIC ACID 1,2,3,4-Tetrahydro-6,7-dimethoxy-3-isoquinolinecarboxylic acid hydrochloride H-DL-TIC-OH (R)-1,2,3,4-TETRAHYDRO-3-ISOQUINOLINECARBOXYLIC ACID METHYL ESTER