Eg5 Inhibitor VII synthesis
- Product Name:Eg5 Inhibitor VII
- CAS Number:912953-25-4
- Molecular formula:C16H12F3NO
- Molecular Weight:291.27
3279-90-1
150 suppliers
$10.00/1g
128796-39-4
423 suppliers
$10.00/5g
912953-25-4
4 suppliers
inquiry
Yield:912953-25-4 85%
Reaction Conditions:
with potassium carbonate;tetrakis(triphenylphosphine) palladium(0) in 1,4-dioxane;water at 90; for 20 h;
Steps:
12
6-(4-TrifluoromethylphenylV3.4-dihvdro-1 H-αuinolin-2-one A mixture of 6-bromo-3,4-dihydro-1 H-quinolin-2-one (0.226 g, 1.00 mmol), 4-(trifluoromethyl)phenylboronic acid (0.380 g, 2.0 mmol), tetrakis(triphenylphosphine)palladium (0) (0.065 g, 0.056 mmol), 2M aqueous EPO
References:
WO2006/113432,2006,A2 Location in patent:Page/Page column 44-45