![](/CAS/GIF/17687-47-7.gif)
Ethanone, 1-[4-(methylamino)phenyl]- (9CI) synthesis
- Product Name:Ethanone, 1-[4-(methylamino)phenyl]- (9CI)
- CAS Number:17687-47-7
- Molecular formula:C9H11NO
- Molecular Weight:149.19
![4'-Bromoacetophenone](/CAS/GIF/99-90-1.gif)
99-90-1
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$6.00/25g
![Methylamine](/CAS/GIF/74-89-5.gif)
74-89-5
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$13.44/25ML
![Ethanone, 1-[4-(methylamino)phenyl]- (9CI)](/CAS/GIF/17687-47-7.gif)
17687-47-7
75 suppliers
$16.00/100mg
Yield: 94%
Reaction Conditions:
with copper in water at 100; for 18 h;
Steps:
To the pressure-resistant tube was added 4-bromoacetophenone 5 g (25.12 mmol), copper powder 0.08 g (1.26 mmol) aqueous methylamine solution (13 mL, 30%). The pressure tube seal was heated to 100 ° C in an oil bath for 18 h, and the reaction solution was cooled to room temperature, then extracted with ethyl acetate (3×100 mL), the organic phase was combined, washed with brine, dried over anhydrous sodium sulfate Development solvent petroleum ether: ethyl acetate = 5:1, 200-300 mesh silica gel column chromatography to give compound 33.53 g, yield 94%
References:
Tianjin University of Science and Technology;Teng Yuou;Xiang Cen;Cao Menglin;Gao Feng;Cui Shanshan;Rong Yao;Zhao Lianbo;Hao Lei;Wang Dong;Yu Peng CN110143890, 2019, A Location in patent:Paragraph 0047
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$7.29/5ml-f
![4-Aminoacetophenone](/CAS/GIF/99-92-3.gif)
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511 suppliers
$6.00/10g
![Ethanone, 1-[4-(methylamino)phenyl]- (9CI)](/CAS/GIF/17687-47-7.gif)
17687-47-7
75 suppliers
$16.00/100mg
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99-92-3
511 suppliers
$6.00/10g
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$15.00/10g
![Ethanone, 1-[4-(methylamino)phenyl]- (9CI)](/CAS/GIF/17687-47-7.gif)
17687-47-7
75 suppliers
$16.00/100mg
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$10.00/25g
![4-Aminoacetophenone](/CAS/GIF/99-92-3.gif)
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$6.00/10g
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inquiry
![Ethanone, 1-[4-(methylamino)phenyl]- (9CI)](/CAS/GIF/17687-47-7.gif)
17687-47-7
75 suppliers
$16.00/100mg
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2124-31-4
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$5.00/1g
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1000210-73-0
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68-11-1
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3406-75-5
32 suppliers
$60.00/50mg
![Ethanone, 1-[4-(methylamino)phenyl]- (9CI)](/CAS/GIF/17687-47-7.gif)
17687-47-7
75 suppliers
$16.00/100mg