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96437-60-4

ethyl 2-(1H-inden-2-yl)acetate synthesis

3synthesis methods
-

Yield:96437-60-4 49.5%

Reaction Conditions:

Stage #1: diethoxyphosphoryl-acetic acid ethyl esterwith sodium hydride in tetrahydrofuran at 10 - 20; for 1.5 h;
Stage #2: 2-indanone in tetrahydrofuran at 0 - 20; for 1.5 h;
Stage #3: with water at 20;

References:

US6339135,2002,B1 Location in patent:Page column 23