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ChemicalBook CAS DataBase List Ethyl 3-tert-butyl-1H-pyrazole-5-carboxylate

Ethyl 3-tert-butyl-1H-pyrazole-5-carboxylate synthesis

6synthesis methods
-

Yield:916791-97-4 85%

Reaction Conditions:

Stage #1: 3,3-dimethyl-butan-2-one;oxalic acid diethyl esterwith sodium ethanolate in ethanol at 20; for 20 h;
Stage #2: with acetic acid;hydrazine in ethanol at 20; for 20 h;

References:

Musatov;Starodubtseva;Rakishev;Turova;Vinogradov [Russian Journal of Organic Chemistry,2011,vol. 47,# 8,p. 1199 - 1203] Location in patent:experimental part