Exalamide synthesis
1synthesis methods
- Product Name:Exalamide
- CAS Number:53370-90-4
- Molecular formula:C13H19NO2
- Molecular Weight:221.3
Yield: 56%
Reaction Conditions:
with tris-(dibenzylideneacetone)dipalladium(0);(2R)-1-[(1R)-1-[bis(1,1-dimethylethyl)phosphino]ethyl]-2-(diphenylphosphino)ferrocene;ammonium carbamate;sodium hydrogencarbonate in 1,4-dioxane at 100; for 20 h;Inert atmosphere;
References:
Nielsen, Dennis U.;Taaning, Rolf H.;Lindhardt, Anders T.;Gogsig, Thomas M.;Skrydstrup, Troels [Organic Letters,2011,vol. 13,# 16,p. 4454 - 4457] Location in patent:supporting information; experimental part