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ChemicalBook CAS DataBase List Flutonidine

Flutonidine synthesis

1synthesis methods
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Yield:-

Steps:

20 EXAMPLE 20

EXAMPLE 20 Using a procedure analogous to that described in Example 19, 36.1% of theory of 1-propargyl-2-[N-(2'-methyl- 5'-fluoro-phenyl)-amino]-2-imidazoline, m.p. 84°-85° C., was obtained from 2-[N-(2'-methyl-5'-fluoro-phenyl)-amino]-2-imidazoline, sodium hydride and propargyl bromide.

References:

US4025607,1977,A

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