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ChemicalBook CAS DataBase List Fmoc-Lys(Trt)-OH

Fmoc-Lys(Trt)-OH synthesis

4synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 4 steps
1: CHCl3; acetonitrile / 2 h / Heating
2: 1.) Et3N / 1.) chloroform, CH3CN, 30 min, RT; 2.) 2 h, RT
3: 77 percent / CH2Cl2 / 0.05 h / 0 °C
4: 58 percent / 10percent Na2CO3 / dioxane / 1.) 1h, 0 deg C, 2.) 12h, room temperature

References:

Barlos, Kleomenis;Mamos, Petros;Papaioannou, Dionysios;Patrianakou, Stella;Sanida, Chariklia;Schaefer, Wolfram [Liebigs Annalen der Chemie,1987,p. 1025 - 1030]

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