FTI-2153 synthesis
- Product Name:FTI-2153
- CAS Number:344900-92-1
- Molecular formula:C25H30N4O3S
- Molecular Weight:466.6
![(S)-methyl 2-(5-(aminomethyl)-2-methyl-[1,1-biphenyl]-2-ylcarboxamido)-4-(methylthio)butanoate(WXG00310)](/CAS/20210111/GIF/722454-00-4.gif)
Yield:344900-92-1 54%
Reaction Conditions:
Stage #1: 2-[(5-aminomethyl-2'-methylbiphenyl-2-carbonyl)amino]-4-methylsulfanylbutyric acid methyl ester;4(5)formylimidazole in methanol at 20; for 0.5 h;
Stage #2: with sodium tetrahydroborate in methanol; for 36 h;
References:
Carrico, Dora;Ohkanda, Junko;Kendrick, Howard;Yokoyama, Kohei;Blaskovich, Michelle A.;Bucher, Cynthia J.;Buckner, Frederick S.;Van Voorhis, Wesley C.;Chakrabarti, Debopam;Croft, Simon L.;Gelb, Michael H.;Sebti, Sa?d M.;Hamilton, Andrew D. [Bioorganic and Medicinal Chemistry,2004,vol. 12,# 24,p. 6517 - 6526]
![methyl 5-cyano-2-methyl-[1,1-biphenyl]-2-carboxylate(WXG00306)](/CAS/20180629/GIF/478908-75-7.gif)
478908-75-7
1 suppliers
inquiry
344900-92-1
8 suppliers
inquiry
16426-64-5
155 suppliers
$5.00/250mg
344900-92-1
8 suppliers
inquiry
100959-22-6
138 suppliers
$14.00/1g
344900-92-1
8 suppliers
inquiry
![[1,1'-Biphenyl]-2-carboxylic acid, 2'-methyl-5-nitro-, methyl ester](/CAS/20200515/GIF/191103-87-4.gif)
191103-87-4
0 suppliers
inquiry
344900-92-1
8 suppliers
inquiry