ChemicalBook CAS DataBase List GNF5

GNF5 synthesis

1synthesis methods

Product Name:GNF5
CAS Number:778277-15-9
Molecular formula:C20H17F3N4O3
Molecular Weight:418.37

Benzoic acid, 3-[6-[[4-(trifluoromethoxy)phenyl]amino]-4-pyrimidinyl]-

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141-43-5 Synthesis

141-43-5
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778277-15-9
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$29.00/5mg

Yield: 80%

Reaction Conditions:

with benzotriazol-1-ol;1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride;N-ethyl-N,N-diisopropylamine in N,N-dimethyl-formamide at 0 - 20;

References:

Deng, Xianming;Okram, Barun;Ding, Qiang;Zhang, Jianming;Choi, Yongmun;Adrian, Francisco J.;Wojciechowski, Amy;Zhang, Guobao;Che, Jianwei;Bursulaya, Badry;Cowan-Jacob, Sandra W.;Rummel, Gabriele;Sim, Taebo;Gray, Nathanael S. [Journal of Medicinal Chemistry,2010,vol. 53,# 19,p. 6934 - 6946] Location in patent:experimental part

GNF5 Related Search:

Indometacin GNF-2 Panobinostat BenzaMide, N-[3-[1,4-dihydro-1-Methyl-7-[(6-Methyl-3-pyridinyl)aMino]-2-oxopyriMido[4,5-d]pyriMidin-3(2H)-yl]-4-Methylphenyl]-3-(trifluoroMethyl)-