GZD856 synthesis
- Product Name:GZD856
- CAS Number:1257628-64-0
- Molecular formula:C29H27F3N6O
- Molecular Weight:532.56
90347-66-3
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1257628-64-0
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Yield:-
Steps:
Multi-step reaction with 3 steps
1.1: copper(l) iodide; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; triethylamine / acetonitrile / 2 h / 80 °C / Inert atmosphere
1.2: 3 h / 20 °C / Inert atmosphere
2.1: copper(l) iodide; N-ethyl-N,N-diisopropylamine; bis-triphenylphosphine-palladium(II) chloride / N,N-dimethyl-formamide / 80 °C / Inert atmosphere
3.1: potassium tert-butylate / tetrahydrofuran / 9 h / -20 - 20 °C
References:
Lu, Xiaoyun;Zhang, Zhang;Ren, Xiaomei;Wang, Deping;Ding, Ke [Journal of Enzyme Inhibition and Medicinal Chemistry,2017,vol. 32,# 1,p. 331 - 336]
694499-26-8
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1429617-97-9
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1257628-64-0
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