Hematin synthesis

Yield:-

Steps:

Multi-step reaction with 3 steps
1: hemY from Bacillus subtilis; oxygen / Enzymatic reaction
2: ferrochelatase from Bacillus subtilis / Enzymatic reaction
3: chlorite dismutase from Staphylococcus aureus / Enzymatic reaction

References:

Dailey, Harry A.;Gerdes, Svetlana;Dailey, Tamara A.;Burch, Joseph S.;Phillips, John D. [Proceedings of the National Academy of Sciences of the United States of America,2015,vol. 112,# 7,p. 2210 - 2215]