![](/CAS/GIF/1074-86-8.gif)
Indole-4-carboxaldehyde synthesis
- Product Name:Indole-4-carboxaldehyde
- CAS Number:1074-86-8
- Molecular formula:C9H7NO
- Molecular Weight:145.16
![INDOLE-4-METHANOL](/CAS/GIF/1074-85-7.gif)
1074-85-7
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![TETRAPROPYLAMMONIUM PERRUTHENATE](/CAS/GIF/114615-82-6.gif)
114615-82-6
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![Indole-4-carboxaldehyde](/CAS/GIF/1074-86-8.gif)
1074-86-8
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Yield:1074-86-8 80%
Reaction Conditions:
with 4-methylmorpholine N-oxide;silica gel in dichloromethane
Steps:
38.B Example 38
Step B: Tetrapropylammonium perruthenate (0.3 g, 0.85 mmol) was added in portions to a mixture of alcohol product from Step A (2.5 g, 17 mmol), N-methylmorpholine N-oxide (3.0 g, 25 mmol) and 4 A molecular sieves (3.0 g) in anhydrous methylene chloride (30 mL) at room temperature. The mixture was stirred at room temperature under nitrogen for 1 h and then filtered. The filtrate was concentrated in vacuo, and the residue was purified by chromatography (SiO2, CH2Cl2) to provide indole-4-aldehyde as a white powder (2.0 g, 80%): 1H NMR (300 MHz, CDCl3) δ 10.2 (s, 1H), 8.52 (br s, 1H), 7.64-7.69 (m, 2H), 7.31-7.44 (m, 3H); CI MS m/z=146 [C9H7NO+H]+.
References:
Beck, James P.;Pechulis, Anthony D.;Harms, Arthur E. US2002/91134, 2002, A1
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1074-85-7
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$27.00/250mg
![Indole-4-carboxaldehyde](/CAS/GIF/1074-86-8.gif)
1074-86-8
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$10.00/1g
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16136-52-0
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1074-86-8
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39830-66-5
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![Indole-4-carboxaldehyde](/CAS/GIF/1074-86-8.gif)
1074-86-8
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3468-22-2
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![Indole-4-carboxaldehyde](/CAS/GIF/1074-86-8.gif)
1074-86-8
293 suppliers
$10.00/1g