ChemicalBook CAS DataBase List Itraconazole Impurity 24

Itraconazole Impurity 24 synthesis

7synthesis methods

Product Name:Itraconazole Impurity 24
CAS Number:79538-91-3
Molecular formula:C21H25N5O2
Molecular Weight:379.46

3H-1,2,4-Triazol-3-one, 2,4-dihydro-4-[4-[4-(4-methoxyphenyl)-1-piperazinyl]phenyl]-2-propyl-

74852-92-9
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79538-91-3
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Yield:79538-91-3 97%

Reaction Conditions:

with water;hydrogen bromide at 110; for 6 h;Inert atmosphere;

References:

Shi, Wei;Nacev, Benjamin A.;Aftab, Blake T.;Head, Sarah;Rudin, Charles M.;Liu, Jun O. [Journal of Medicinal Chemistry,2011,vol. 54,# 20,p. 7363 - 7374] Location in patent:supporting information; experimental part

38212-30-5
203 suppliers
$15.00/5G

79538-91-3
12 suppliers
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References

1-(4-Methoxyphenyl)-4-(4-nitrophenyl)piperazine

74852-61-2
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79538-91-3
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References

74853-07-9 Synthesis

2,4-dihydro-4-[4-[4-(4-methoxyphenyl)piperazin-1-yl]phenyl]-3H-1,2,4-triazol-3-one

74853-07-9
53 suppliers
$55.00/10mg

79538-91-3
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References

1-(4-AMINOPHENYL)-4-(4-METHOXYPHENYL)PIPERAZINE

74852-62-3
150 suppliers
$26.57/5G

79538-91-3
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References

Itraconazole Impurity 24 Related Search:

Itraconazole 2,4-DIHYDRO-4-[(4-(4-HYDROXYPHENYL)-1-PIPERAZINYL)PHENYL]-2-(1-METHYLPROPYL)-3H-1,2,4-TRIAZOLE-3-ONE cis-2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolane-4-methanol Isopropyl Itraconazole