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ChemicalBook CAS DataBase List cis-2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolane-4-methanol

cis-2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolane-4-methanol synthesis

5synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 3 steps
1: 50 percent / pyridine / 3 h / 5 °C
2: NaH / paraffin; dimethylsulfoxide / 1.) room temperature, 1 h, 2.) 130 deg C, 12 h
3: 55 percent / 5 N NaOH / dioxane; H2O / 2 h / Heating

References:

Baji;Kimny, Tan;Gasquez;Flammang;Compagnon;Delcourt;Mathieu;Viossat;Morgant;Nguyen-Huy [European Journal of Medicinal Chemistry,1997,vol. 32,# 7-8,p. 637 - 650]

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