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ChemicalBook CAS DataBase List japonine
30426-61-0

japonine synthesis

2synthesis methods
-

Yield:30426-61-0 90 %

Reaction Conditions:

Stage #1: 3-hydroxy-6-methoxy-2-phenylquinolin-4(1H)-onewith sodium hydride in tetrahydrofuran at 0;
Stage #2: methyl iodide in tetrahydrofuran at 0;

References:

Dutta, Lona;Ramasastry [Organic Letters,2022,vol. 24,# 41,p. 7665 - 7670] Location in patent:supporting information