japonine synthesis
2synthesis methods
- Product Name:japonine
- CAS Number:30426-61-0
- Molecular formula:C18H17NO3
- Molecular Weight:295.33
Yield:30426-61-0 90 %
Reaction Conditions:
Stage #1: 3-hydroxy-6-methoxy-2-phenylquinolin-4(1H)-onewith sodium hydride in tetrahydrofuran at 0;
Stage #2: methyl iodide in tetrahydrofuran at 0;
References:
Dutta, Lona;Ramasastry [Organic Letters,2022,vol. 24,# 41,p. 7665 - 7670] Location in patent:supporting information
