![](/CAS/GIF/2788-84-3.gif)
L-SERINE METHYL ESTER synthesis
- Product Name:L-SERINE METHYL ESTER
- CAS Number:2788-84-3
- Molecular formula:C4H9NO3
- Molecular Weight:119.12
![Methanol](/CAS/GIF/67-56-1.gif)
67-56-1
739 suppliers
$7.29/5ml-f
![L-Serine](/CAS/GIF/56-45-1.gif)
56-45-1
740 suppliers
$5.00/25g
![L-SERINE METHYL ESTER](/CAS/GIF/2788-84-3.gif)
2788-84-3
29 suppliers
$367.00/0.25G
Yield:2788-84-3 98%
Reaction Conditions:
with thionyl chloride
Steps:
Following the synthetic route depicted below the L-amino acids were treated with methanol and sulfoxide chloride to convert into the corresponding L-amino acid methyl esters II (98% yield) in the present invention. The methyl esters IIa-d were acylated by use of benzoyl chloride and N-benzoyl-L-amino acid methyl esters of IIIa-d were obtained (81% yield). Using sodium borohydride as the reduction agent the benzoylated methyl esters were reduced to N-benzoylaminoglycols IVa-d successfully (97% yield).
References:
Zen, Hayley;Peng, Shiqi;Bi, Lanrong;Zhao, Ming;Wang, Chao US2005/43396, 2005, A1 Location in patent:Page/Page column 3
![N-Cbz-L-serine methyl ester](/CAS/GIF/1676-81-9.gif)
1676-81-9
183 suppliers
$15.00/1g
![L-SERINE METHYL ESTER](/CAS/GIF/2788-84-3.gif)
2788-84-3
29 suppliers
$367.00/0.25G
![L-Serine methyl ester hydrochloride](/CAS/GIF/5680-80-8.gif)
5680-80-8
445 suppliers
$10.00/5g
![L-SERINE METHYL ESTER](/CAS/GIF/2788-84-3.gif)
2788-84-3
29 suppliers
$367.00/0.25G
![Boc-L-serine methyl ester](/CAS/GIF/2766-43-0.gif)
2766-43-0
294 suppliers
$10.00/1g
![L-SERINE METHYL ESTER](/CAS/GIF/2788-84-3.gif)
2788-84-3
29 suppliers
$367.00/0.25G
![L-Serine](/CAS/GIF/56-45-1.gif)
56-45-1
740 suppliers
$5.00/25g
![L-SERINE METHYL ESTER](/CAS/GIF/2788-84-3.gif)
2788-84-3
29 suppliers
$367.00/0.25G