METHYL 2-DIBENZOFURANCARBOXYLATE synthesis

8synthesis methods

Product Name:METHYL 2-DIBENZOFURANCARBOXYLATE
CAS Number:58841-72-8
Molecular formula:C14H10O3
Molecular Weight:226.23

67-56-1 Synthesis

67-56-1
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$9.00/25ml

22439-48-1
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$57.50/250mg

58841-72-8
7 suppliers
$106.00/50mg

Yield:58841-72-8 650 mg

Reaction Conditions:

with thionyl chloride at 80; for 4 h;

Steps:

24.24b Step 24b: Preparation of diphenyl[b,d]furan-2-carboxylate (compound 0603-96):

The compound diphenyl[b,d]furan-2-carboxylic acid (0602-96)(1.2g, 5.66 mmol, 1.0 eq)Dissolved in 50 ml of methanol,Cool in an ice bath and slowly add thionyl chloride (0.82 mL, 11.3 mmol, 2.0 equiv).Heat to 80°C and react for 4 hours.After the reaction was completed, it was concentrated under reduced pressure.Dissolve the residue in twoIn methyl chloride, saturated sodium bicarbonate solution was added and the solution was made alkaline to separate the solution. The organic phase was dried over anhydrous sodium sulfate, and spin-dry. The residue was purified by silica gel column chromatography (eluent: ethyl acetate/petroleum ether=1/5) to give the product dibenzo[b,d]furan-2-one carboxylic acidMethyl ester (650 mg, yield: 55%).

References:

CN107383024,2017,A Location in patent:Paragraph 0279

15126-06-4 Synthesis