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ChemicalBook CAS DataBase List Methyl 3-methyl-5-(trifluoromethyl)benzoate

Methyl 3-methyl-5-(trifluoromethyl)benzoate synthesis

1synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1: (1,5-cyclooctadiene)(methoxy)iridium(l) dimer; 4,4'-ditert-butyl-2,2'-bipyridine / tetrahydrofuran / 18 h / 80 °C / Inert atmosphere
2: potassium fluoride / N,N-dimethyl-formamide / 18 h / 50 °C / Inert atmosphere

References:

Litvinas, Nichole D.;Fier, Patrick S.;Hartwig, John F. [Angewandte Chemie - International Edition,2012,vol. 51,# 2,p. 536 - 539]

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