METHYL 3-(THIEN-2-YL)ACRYLATE synthesis
10synthesis methods
- Product Name:METHYL 3-(THIEN-2-YL)ACRYLATE
- CAS Number:57502-38-2
- Molecular formula:C8H8O2S
- Molecular Weight:168.21
Yield:57502-38-2 98%
Reaction Conditions:
Stage #1: trimethyl phosphonoacetatewith sodium hydride in tetrahydrofuran at 20; for 0.0833333 h;Horner-Wadsworth-Emmons Olefination;
Stage #2: thiophene-2-carbaldehyde in tetrahydrofuran at 20; for 15 h;Horner-Wadsworth-Emmons Olefination;
References:
Bengtsson, Christoffer;Nelander, Hanna;Almqvist, Fredrik [Chemistry - A European Journal,2013,vol. 19,# 30,p. 9916 - 9922]
