![](/CAS/GIF/10165-86-3.gif)
METHYL 6-FORMYLNICOTINATE synthesis
- Product Name:METHYL 6-FORMYLNICOTINATE
- CAS Number:10165-86-3
- Molecular formula:C8H7NO3
- Molecular Weight:165.15
![Methyl 6-(hydroxymethyl)nicotinate](/CAS/GIF/56026-36-9.gif)
56026-36-9
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$9.00/100mg
![METHYL 6-FORMYLNICOTINATE](/CAS/GIF/10165-86-3.gif)
10165-86-3
117 suppliers
$22.00/100mg
Yield:10165-86-3 97%
Reaction Conditions:
with manganese(IV) oxide in dichloromethane at 20; for 4 h;
Steps:
c (c) methyl 6-formylnicotinate
A mixture of methyl 6-(hydroxymethyl)nicotinate (7 g , 37 mmol) and Mn02 (32,3 g , 372 mmol) in DCM ( 200 mL ) was stirred at 20 °C for 4 hours. The mixture was filtered and the filtrate was concentrated. The residue was purified by column chromatography on silica gel (PE/EtOAc = 5/1) to afford methyl 6-formylnicotinate (6 g , 97%).MS-ESI (m/z): 166.2 (M+l) + (LC-MS method C; Ret. time: 0.36 min).
References:
WO2014/114185,2014,A1 Location in patent:Page/Page column 126
![Methyl 6-methylnicotinate](/CAS/GIF/5470-70-2.gif)
5470-70-2
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$5.00/5g
![METHYL 6-FORMYLNICOTINATE](/CAS/GIF/10165-86-3.gif)
10165-86-3
117 suppliers
$22.00/100mg
![5-(Methoxycarbonyl)pyridine-2-carboxylic acid](/CAS/GIF/17874-79-2.gif)
17874-79-2
126 suppliers
$15.00/1g
![METHYL 6-FORMYLNICOTINATE](/CAS/GIF/10165-86-3.gif)
10165-86-3
117 suppliers
$22.00/100mg
![methyl 6-(dibromomethyl)pyridine-3-carboxylate](/CAS/20180629/GIF/1001200-43-6.gif)
1001200-43-6
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![METHYL 6-FORMYLNICOTINATE](/CAS/GIF/10165-86-3.gif)
10165-86-3
117 suppliers
$22.00/100mg
![3-Pyridinecarboxylic acid, 6-[(diethylamino)carbonyl]-, methyl ester](/CAS/20210305/GIF/932382-16-6.gif)
932382-16-6
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![METHYL 6-FORMYLNICOTINATE](/CAS/GIF/10165-86-3.gif)
10165-86-3
117 suppliers
$22.00/100mg