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18162-48-6872-50-4Methylene ChloridenaphthaleneTHFTitanium Dioxide
ChemicalBook CAS DataBase List Milfasartan
148564-47-0

Milfasartan synthesis

10synthesis methods
1918-78-1 Synthesis
2-METHYL-THIOPHENE-3-CARBOXYLIC ACID

1918-78-1
81 suppliers
$9.00/250mg

Milfasartan

148564-47-0
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-

Yield:-

Steps:

Multi-step reaction with 4 steps
1: H2SO4
2: 75 percent / N-bromosuccinimide, α,α'-azoisobutyronitrile / CCl4 / 3 h / 70 °C
3: 1.) NaH, 2.) LiBr
4: 37 percent / NaN3, tributyltin chloride / toluene / 60 h / Heating

References:

Salimbeni, Aldo;Canevotti, Renato;Paleari, Fabio;Poma, Davide;Caliari, Saturnino;et al. [Journal of Medicinal Chemistry,1995,vol. 38,# 24,p. 4806 - 4820]

172292-52-3 Synthesis
Methyl 2-((4-butyl-5-((2'-cyano-[1,1'-biphenyl]-4-yl)methyl)-2-methyl-6-oxopyrimidin-1(6H)-yl)methyl)thiophene-3-carboxylate

172292-52-3
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Milfasartan

148564-47-0
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References
53562-51-9 Synthesis
2-Methyl-3-thiophenecarboxylic acid methyl ester

53562-51-9
78 suppliers
$52.00/1g

Milfasartan

148564-47-0
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References
39815-78-6 Synthesis
METHYL 3-OXOHEPTANOATE

39815-78-6
111 suppliers
$91.67/25g

Milfasartan

148564-47-0
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References
2-(bromomethyl)-3-Thiophenecarboxylic acid methyl ester

88048-78-6
8 suppliers
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Milfasartan

148564-47-0
11 suppliers
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References

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