ChemicalBook CAS DataBase List N-(4-Bromobutyl)phthalimide

N-(4-Bromobutyl)phthalimide synthesis

10synthesis methods

Product Name:N-(4-Bromobutyl)phthalimide
CAS Number:5394-18-3
Molecular formula:C12H12BrNO2
Molecular Weight:282.13

110-52-1 Synthesis

110-52-1
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1074-82-4
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$5.00/25g

5394-18-3
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Yield:5394-18-3 92.4%

Reaction Conditions:

in N,N-dimethyl-formamide; pH=10 at 20; for 26 h;

Steps:

1.4 preparation of intermediate 4
The phthalimide potassium salt (2.0g, 10 . 7mmol) with 1, 4 - dibromo butane (2.8g, 12 . 9mmol) dissolved in 25 ml dry N,N-dimethylformamide in, for pH 10, room temperature stirring 26h. Dichloromethane is used for extraction three times (100 ml × 3), washed with distilled water, combined with the organic layer, drying by anhydrous magnesium sulphate, concentrated, dichloromethane/distilled water recrystallization, filtering, drying to obtain the white solid, yield of 92.4%.

References:

Shandong University;Du Lvpei;Li Minyong;Wang Beilei CN104910894, 2017, B Location in patent:Paragraph 0032; 0034; 0042; 0043

110-52-1 Synthesis

110-52-1
552 suppliers
$9.00/1g