![](/CAS/GIF/24068-29-9.gif)
N-(4-Nitrophenyl)pyridin-2-amine synthesis
- Product Name:N-(4-Nitrophenyl)pyridin-2-amine
- CAS Number:24068-29-9
- Molecular formula:C11H9N3O2
- Molecular Weight:215.21
![2-Aminopyridine](/CAS/GIF/504-29-0.gif)
504-29-0
541 suppliers
$5.00/5G
![1-Bromo-4-nitrobenzene](/CAS/GIF/586-78-7.gif)
586-78-7
9 suppliers
$14.00/5g
![N-(4-Nitrophenyl)pyridin-2-amine](/CAS/GIF/24068-29-9.gif)
24068-29-9
14 suppliers
$184.00/250mg
Yield:24068-29-9 76%
Reaction Conditions:
with potassium tert-butylate in dimethylsulfoxide-d6 at 60; for 5 h;
Steps:
Synthesis of compounds (1a-l); general procedure
General procedure: A mixture of the appropriate N-nucleophile (2 mmol), 4-bromonitrobenzene(2 mmol), t-ButOK or KOH (in the case of 1g, 1h)(2.2 mmol) in dimethyl sulfoxide (2.5 mL) was stirred at 60 °C for 5 h(8 h in the case of 1b). After cooling and addition of water (60 mL),either a solid precipitated which was filtered, washed with water andrecrystallised from an appropriate solvent to give the product, or asuspension was generated which was extracted with ethyl acetate(3 × 30 mL), dried over Na2SO4, concentrated under reduced pressureand recrystallised from an appropriate solvent to give the desiredproduct
References:
Ghasemi, Zarrin;Shahrak, Nasim Shahi;Roomi, Behzad Jalali;Zakeri, Ziba [Journal of Chemical Research,2015,vol. 39,# 2,p. 73 - 75]
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$278.00/5g
![1-Bromo-4-nitrobenzene](/CAS/GIF/586-78-7.gif)
586-78-7
9 suppliers
$14.00/5g
![N-(4-Nitrophenyl)pyridin-2-amine](/CAS/GIF/24068-29-9.gif)
24068-29-9
14 suppliers
$184.00/250mg
![2-Bromopyridine](/CAS/GIF/109-04-6.gif)
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$6.00/25g
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![N-(4-Nitrophenyl)pyridin-2-amine](/CAS/GIF/24068-29-9.gif)
24068-29-9
14 suppliers
$184.00/250mg
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$11.19/25G
![N-(4-Nitrophenyl)pyridin-2-amine](/CAS/GIF/24068-29-9.gif)
24068-29-9
14 suppliers
$184.00/250mg
![2-Aminopyridine](/CAS/GIF/504-29-0.gif)
504-29-0
541 suppliers
$5.00/5G
![4-Fluoronitrobenzene](/CAS/GIF/350-46-9.gif)
350-46-9
513 suppliers
$10.60/1gm:
![N-(4-Nitrophenyl)pyridin-2-amine](/CAS/GIF/24068-29-9.gif)
24068-29-9
14 suppliers
$184.00/250mg