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ChemicalBook CAS DataBase List N-Acetyl-3-(2,6-difluoro-phenyl)-D-alanine
266360-56-9

N-Acetyl-3-(2,6-difluoro-phenyl)-D-alanine synthesis

3synthesis methods
85118-00-9 Synthesis
2,6-Difluorobenzyl bromide

85118-00-9
332 suppliers
$6.00/1g

-

Yield:-

Steps:

Multi-step reaction with 4 steps
1: 90 percent / NaOEt / ethanol / 2 h / Heating
2: 2M NaOH / methanol; H2O / 3 h / 40 °C
3: 92 percent / p-xylene / 2 h / Heating
4: Aspergillus genus acylase; 0.2 M AcONa; 0.2 M NaOH / H2O / 48 h / 38 °C / pH 8.0

References:

Fujita, Tsugumi;Nose, Takeru;Matsushima, Ayami;Okada, Kazushi;Asai, Daisuke;Yamauchi, Yasuko;Shirasu, Naoto;Honda, Takeshi;Shigehiro, Daiki;Shimohigashi, Yasuyuki [Tetrahedron Letters,2000,vol. 41,# 6,p. 923 - 927]

266360-50-3 Synthesis
2-acetaMido-3-(2,6-difluorophenyl)propaNAic acid

266360-50-3
13 suppliers
inquiry

33787-05-2 Synthesis
DL-2,6-DIFLUOROPHENYLALANINE

33787-05-2
78 suppliers
$34.00/250mg