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ChemicalBook CAS DataBase List N-BOC-4-HYDROXYINDOLE

N-BOC-4-HYDROXYINDOLE synthesis

2synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 3 steps
1: potassium carbonate / acetone / 12 h / Inert atmosphere; Reflux
2: triethylamine / acetonitrile / 12 h / 20 °C / Inert atmosphere
3: bis(pinacol)diborane; (1,2-dimethoxyethane)dichloronickel(II); 6,6'-dimethyl-2,2'-bipyridine; lithium tert-butoxide / N,N-dimethyl acetamide; water; methanol / 24 h / 30 °C / Inert atmosphere; Glovebox; Sealed tube

References:

Meng, Chenkai;Niu, Haolin;Ning, Juehan;Wu, Wengang;Yi, Jun [Molecules,2020,vol. 25,# 3,art. no. 602]

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