N,N-DIMETHYL 3-NITROBENZENESULFONAMIDE synthesis
- Product Name:N,N-DIMETHYL 3-NITROBENZENESULFONAMIDE
- CAS Number:26199-83-7
- Molecular formula:C8H10N2O4S
- Molecular Weight:230.24
Yield:26199-83-7 96%
Reaction Conditions:
with triethylamine in acetonitrile at 25; for 24 h;
Steps:
10.1-10.2 Preparation method of compound 3j:
(1) 1 mmol of latinosyl N, N-dimethylamino-3-methylindole shown in Formula 1, 1.5 mmol of 3-nitrobenzenesulfonyl chloride as shown in Formula 2j was added to a 50 mL flask, Add 10mL of CH3CN to completely dissolve, Slowly add 1.5 mmol of Et3N, and stir the reaction at 25 ° C for 24h to obtain a reaction solution; The reaction is as follows: (2) The reaction solution was concentrated under reduced pressure, CH2Cl2 and water were added, and the organic phases were combined. It was washed with saturated brine and dried over anhydrous sodium sulfate. The solvent was concentrated and evaporated to dryness, and then separated by silica gel column chromatography to obtain N, N-dimethylsulfonamide derivatives as shown in Formula 3j.
References:
CN110240533,2019,A Location in patent:Paragraph 0106-0110; 0172
121-51-7
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$15.00/5G
26199-83-7
20 suppliers
$75.00/500mg
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121-51-7
9 suppliers
$15.00/5G
26199-83-7
20 suppliers
$75.00/500mg