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N-TERT-BUTYL-2-PIPERAZIN-1-YL-NICOTINAMIDE synthesis

3synthesis methods
110-85-0 Synthesis
Piperazine

110-85-0
554 suppliers
$5.00/5G

144084-34-4 Synthesis
N-(tert-Butyl)-2-chloronicotinamide

144084-34-4
13 suppliers
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N-TERT-BUTYL-2-PIPERAZIN-1-YL-NICOTINAMIDE

153473-72-4
3 suppliers
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Yield:153473-72-4 91%

Reaction Conditions:

with potassium carbonate in acetonitrile; for 24 h;Heating;

References:

Romero;Morge;Biles;Berrios-Pena;May;Palmer;Johnson;Smith;Busso;Tan;Voorman;Reusser;Althaus;Downey;So;Resnick;Tarpley;Aristoff [Journal of Medicinal Chemistry,1994,vol. 37,# 7,p. 999 - 1014]

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