N1,N1-DIETHYL-2-FLUORO-1,4-BENZENEDIAMINE synthesis
- Product Name:N1,N1-DIETHYL-2-FLUORO-1,4-BENZENEDIAMINE
- CAS Number:83800-33-3
- Molecular formula:C10H15FN2
- Molecular Weight:182.24
2689-37-4
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83800-33-3
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$237.00/500mg
Yield: 93%
Reaction Conditions:
with hydrogen;palladium in tetrahydrofuran at 20; for 12 h;
Steps:
8.2 [002771 Step 2) N’, N’-diethyl-2-fluorobenzene- 1 ,4-diamine
To a solution of N,N-diethyl-2-fluoro-4-nitroaniline (4.00 g, 18.84 mmol) in THF (50 mL) was added Pd/C (1.50 g). The reaction mixture was stirred at rt under H2 for 12 h. The mixture was filtered, and the filtrate was concentrated in vacuo to give the title compound as an offwhite solid (3.20 g, 93%).
References:
SUNSHINE LAKE PHARMA CO., LTD.;ZHANG, Yingjun;ZHANG, Jiancun;WANG, Xiaojun;LIN, Runfeng;CAO, Shengtian;WANG, Zhaohe;LI, Jing WO2014/12360, 2014, A1 Location in patent:Paragraph 00277
369-34-6
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83800-33-3
9 suppliers
$237.00/500mg