Norethindrone-3-ethyldienolether synthesis
- Product Name:Norethindrone-3-ethyldienolether
- CAS Number:96487-85-3
- Molecular formula:C22H30O2
- Molecular Weight:326.47
68-22-4
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122-51-0
485 suppliers
$10.00/5ml
96487-85-3
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$130.00/100mg
Yield:96487-85-3 92%
Reaction Conditions:
with toluene-4-sulfonic acid in tetrahydrofuran at 25; for 12 h;Temperature;
Steps:
1.1 1.1 3-ethoxy-17α-ethynyl-19-desmethylpregna-3,5-diene-17β-ol (2)
Compound 1 (15 g, 0.05 mol) was dissolved in THF (150 ml) and added to the reaction flask, Then triethyl orthoformate (14.8 g, 0.1 mol) was added, P-toluenesulfonic acid (0.15 g, 0.8 mmol). The reaction solution was stirred at 25 ° C for 12 hours, Pyridine (3 ml) was added, The majority of the solvent was distilled off under reduced pressure, Cooling filter, Dried product 15g, Yield 92%.
References:
CN105017365,2017,B Location in patent:Paragraph 0031-0033; 0044-0046; 0057-0059
734-32-7
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$300.00/1g
96487-85-3
29 suppliers
$130.00/100mg