P-DECYLOXYNITROBENZENE synthesis

6synthesis methods

Product Name:P-DECYLOXYNITROBENZENE
CAS Number:31657-37-1
Molecular formula:C16H25NO3
Molecular Weight:279.37

112-30-1 Synthesis

112-30-1
455 suppliers
$5.00/25g

100-00-5
8 suppliers
$14.00/25g

31657-37-1
14 suppliers
$106.00/250mg

Yield:31657-37-1 95 %

Reaction Conditions:

with caesium carbonate in toluene at 80;

Steps:

General procedure for C-O cross-coupling reaction:

General procedure: In a reaction tube Pd catalyst (25 mg), Cs₂CO₃(1.2 mmol, 0.165 g), Toluene (2 mL), arylhalide (1 mmol) and alcohol (1.2 mmol) were added and this mixture was heated whilst keep on stirring at 80 °C. After 6h the reaction mixture was stopped and the reaction mixture was cooled at room temperature. The organic layer was extracted in the solution mixture of water and ethylacetate, organic layer was dried under reduced pressure and the resulting residue was subjected for the column chromatographic separation of the final product which was further confirmed by the ¹H NMR and ¹³C NMR spectroscopy.

References:

Khandaka, Himanshu;Kumar Joshi, Raj [Tetrahedron Letters,2022,vol. 111,art. no. 154163] Location in patent:supporting information

100-02-7 Synthesis